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DNA isn’t the simple, loose double-helix you might see in a biology textbook, so isolating single strands of it can be next to impossible. But with some simple tricks of physics, scientists came up with a special type of tweezers that can unzip DNA!
Hosted by: Rose Bear Don’t Walk
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Sources:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00453-6
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-11-5-288
https://www.cambridge.org/core/books/optical-tweezers/introduction/DB937BE06C9CCA79FDA01F43BB312AE5
https://www.pnas.org/content/94/10/4853
https://www.nobelprize.org/uploads/2018/10/ashkin-lecture.pdf
https://www.annualreviews.org/doi/10.1146/annurev.bi.49.070180.005343
https://pubs.acs.org/doi/full/10.1021/cr4003006
https://www.nature.com/articles/s43586-021-00021-6
https://www.sciencedirect.com/science/article/pii/S0092867418315113
Image Sources:
https://www.istockphoto.com/photo/three-tweezers-tweezers-on-a-white-background-gm1262858821-369561418
https://www.storyblocks.com/video/stock/a-young-man-plucking-his-eyebrows-with-tweezers-styling-eyebrows-macro-r05jp9o1fja32nmvz
https://www.storyblocks.com/video/stock/seamless-looping-animation-of-rotating-dna-strands-e1hwm_0cgiks0m37h
https://commons.wikimedia.org/wiki/File:Nucleosome_1KX5_2.png
https://www.storyblocks.com/video/stock/animation-of-genetic-dna-loop-able-4k-rxfbx2wcgizuoo76d
https://www.storyblocks.com/video/stock/floating-cells-multiplying-red-version-lxo-vwt
https://www.istockphoto.com/photo/chromosome-isolated-on-white-background-with-depth-of-field-effect-gm584244506-100036213
https://commons.wikimedia.org/wiki/File:Nucleosome_organization.png
https://commons.wikimedia.org/wiki/File:Nucleosome.png
https://commons.wikimedia.org/wiki/File:Basic_units_of_chromatin_structure.svg
https://commons.wikimedia.org/wiki/File:Sail-Force1.gif
https://commons.wikimedia.org/wiki/File:Worlds_first_laser_out_of_case.jpg
https://commons.wikimedia.org/wiki/File:Military_laser_experiment.jpg
https://commons.wikimedia.org/wiki/File:Femtomolar_Optical_Tweezers_(5881942888).jpg
https://www.istockphoto.com/photo/chromatin-strand-and-isolated-nucleosome-dna-histones-gm1169905740-323575931
https://commons.wikimedia.org/wiki/File:1aoi_nucleosome_rib_round.tif
https://commons.wikimedia.org/wiki/File:Stylized_DNA.png
https://www.storyblocks.com/video/stock/lamp-and-the-books-in-library-2-rag585s9rk2i80i6s
https://commons.wikimedia.org/wiki/File:Table_chamber_GWMorley.jpg
https://www.istockphoto.com/photo/3d-illustration-protein-or-enzyme-gm1138925640-304251159
https://www.storyblocks.com/video/stock/dna-sequencing-the-bases-of-a-fragment-of-dna-abstract-background-skx-uxydpkgvmnshp
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